Credit: Original article published here.Researchers, led by Amara Sarwal, MD, conducted a study to determine whether chronic kidney disease (CKD) and heart failure are independent risk factors for Alzheimer disease/related dementias (ADRD) in a cohort of US veterans with type 2 diabetes. Results were reported during a poster session at the National Kidney Foundation Spring Clinical Meetings 2023 in a poster titled Cardiorenal Syndrome: CKD, Heart Failure, and Risk for Dementia. The cohort included US veterans ≥65 years of age with type 2 diabetes and two outpatient measurements of serum creatinine at least 60 days apart from January 1, 2008, to December 31, 2010. The date of the second creatinine measurement was considered the index date. The CKD Epidemiology Collaboration equation was used to define estimated glomerular filtration rate. International Classification of Diseases, Tenth Revision(ICD 9/10) codes from January 1, 2000, to the index date were used to define the presence of heart failure and other comorbidities. Veterans with ADRD at baseline were excluded. Occurrences of ADRD subsequent to baseline were identified by ICD-9/10 codes from the index date to December 31, 2021. The cohort included 362,598 US veterans. Of those, 14.6% had heart failure at baseline, 34.8% had stage